Which principle focuses on minimizing adverse effects for research participants?

The correct response is grounded in the ethical principle that emphasizes the responsibility of researchers to ensure the safety and well-being of all participants involved in a study. This principle, often referred to as "protection from harm," is crucial in research ethics. It mandates that researchers take all necessary precautions to minimize any physical, psychological, or emotional risks that could potentially arise as a result of participation in research.

This principle is integral to the ethical conduct of research, recognizing that participants should not be subjected to unnecessary risks or harmful situations. By adhering to this principle, researchers demonstrate their commitment to the welfare of participants, which is paramount in establishing trust and integrity in the research process.

Other principles, such as informed consent and beneficence, do contribute to the overall ethical framework but focus on different aspects. Informed consent ensures that participants are fully aware and agree to the nature of the research and any potential risks. Beneficence, while it emphasizes the obligation to maximize benefits and minimize harms, focuses more broadly on the overall positive impact of research rather than the specific protection from harm that is explicitly covered by the selected principle.